Paradigm shifts, especially in medicine, do not happen just because the science or new technologies suggest they should. Based on that assumption, some 20 institutions representing different sectors of the health system founded the Personalized Medicine Coalition in 2003 to improve upon medical paradigms that base treatment decisions exclusively on population averages.

With more than 200 active members, PMC membership is open but not limited to universities and academic medical centers, nonprofit research entities, relevant trade associations, patient advocacy groups, government officials (ex-officio), health care organizations, health care providers, payers, information technology companies, and research-based commercial companies that offer an array of products and services including research tools, diagnostic technologies and products, screening services, and therapeutic interventions.

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